First CRISPR gene therapy approved!

PLUS: Snapchat+ tops $20M

Welcome, Tech enthusiasts.

The FDA just handed a pioneering gene editing treatment landmark approval — harnessing precision DNA snipping to override sickle cell deficiency.

Has the CRISPR revolution officially arrived in the medical world? Let’s find out.

In today’s tech rundown:

  • FDA greenlights landmark first CRISPR treatment

  • Snapchat+ tops $20M revenue

  • 9 new products

  • Google shuts down Beeper’s Android-iMessage integration

  • Elon Musk reinstates Alex Jones to Twitter/X

  • Apple’s USB-C update rumored for Spring 2024

Read time: 3 minutes

TODAY’S HEADLINES

GENE EDITING

Image source: Vertex Pharmaceuticals

The Rundown: The FDA just approved the first ever CRISPR-based treatment in a landmark moment for gene editing — with the therapy set to treat debilitating sickle cell disease.

The details:

  • Called CTX001 or Casgevy, the one-time treatment involves using CRISPR to switch on the production of an alternate "fetal" hemoglobin protein that prevents sickling.

  • It works by cutting out the gene that normally shuts off fetal hemoglobin after birth — allowing it to resume circulating and blocking sickle hemoglobin's damaging effects.

  • In trials, over 90% of patients went 1+ years crisis-free after getting their edited stem cells infused back into the body post-chemo.

Why it matters: Now proven viable, expect a deluge of CRISPR treatments leveraging precision DNA editing to overcome conditions long thought untreatable. Let’s hope this moment kickstarts a healthcare revolution.

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SNAPCHAT

Image source: Snap

The Rundown: Snapchat's paid subscription quietly continued its explosive growth — passing $20M in monthly revenue for the first time in November amid climbing demand for perks like early AI access.

The details:

  • Snapchat+ revenue jumped 23% month-over-month to over $31M before commissions, its second-biggest increase ever.

  • The app now boasts over 5 million subscribers globally, with the top markets for spending including the U.S., UK, France, and Australia.

  • Features like expanded access to the ‘My AI’ chatbot and ‘Dreams’ AI selfies, along with new visual filters, continue to attract fresh sign-ups.

The relevance: While Snapchat may have fallen out of favor with older social media users, there looks to still be serious demand from the younger demographics. And those younger audiences are showing a surprising willingness to pay for digital life enhancements and new AI features.

NEW PRODUCTS

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📘 Ello- An AI-powered reading companion designed to enchant kids with the joy of books (link)

💻 KATA Teams- Enhance your engineering team's productivity with a supportive second screen (link)

💡 Mixo- Launch a startup in seconds with AI (link)

🎵 Mubert- Soundtrack for your content made by AI (link)

🦿 My AskAI- Create your own ChatGPT from your content (link)

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SNIPPETS

Apple shut down Beeper Mini, an app designed to integrate iMessage with Android, citing concerns over security and user privacy exploitation.

Elon Musk conducted a poll on X, and following a majority "Yes" vote, controversial conspiracy theorist Alex Jones has been reinstated after a five-year ban.

A Bluetooth SIG database listing suggests the imminent launch of the Samsung Galaxy Fit 3 fitness tracker.

Apple is rumored to update its Mac accessories with USB-C ports by the spring of 2024, signaling a further retreat from its Lightning connector.

Ford's upcoming collaboration between its F-150 Lightning pickup and Resideo smart thermostats will demonstrate using the EV's battery for powering home AC when grid rates are high.

The Raspberry Pi OS now includes an easy-to-toggle dark mode, protecting your vision during extended use.

Amazon filed a motion to dismiss the FTC's antitrust lawsuit alleging it uses unfair monopolistic tactics — arguing a lack of evidence the company’s practices actually raised prices or harmed consumers.

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THAT’S A WRAP

If you have anything interesting to share, please reach out to us by sending us a DM on Twitter: @rowancheung & @therundowntech

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